Harvey Weinstein and Roger Ailes are among the most famous sexual predators to wreak havoc on their employees, but they are just two of the untold number of abusive bosses who have created horrifically toxic workplaces. In a radical departure from her latest project, “A Beautiful Day in the Neighborhood,” a portrait of universally beloved children’s entertainer Fred Rogers, Marielle Heller will direct and serve as showrunner on a limited series about a serial sexual harasser. She’s reuniting with Big Beach, the producers behind “A Beautiful Day in the Neighborhood,” for “Five Women.” Deadline broke the news.

Based on an episode of NPR’s show and podcast “This American Life,” “Five Women” follows “the lives of several women who have little in common except for their boss, who sexually harasses them,” the source details. “Before those troubling encounters, though, how did their personal histories affect the way they dealt with his harassment? Who they were before they entered the workplace – each woman’s life experience – shapes the way each of them deals with his harassment, in a way that’s rarely discussed or dramatized.”

Chana Joffe-Walt produced and reported the story for “This American Life.”

Heller, whose other credits include Melissa McCarthy-starrer “Can You Ever Forgive Me?” and coming-of-age pic “The Diary of a Teenage Girl,” will exec producer through her new shingle, Defiant by Nature.

Defiant by Nature has a first-look deal with Big Beach that sees Heller developing new series and specials, some of which she’ll direct.

When we asked Heller her advice for other women directors, she urged, “Appreciate those who came before you. Learn what they went through and recognize that because of them, and only because of them, you can be seen and welcomed — and sometimes even respected.”